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A randomized clinical trial of berberine hydrochloride in patients with diarrhea predominant irritable bowel syndrome priligy pills In scenario 1 S1, three different sets of survival curves were used an absolute increase of 20 S1a; 100 on target, 15 S1b; 95 on target or 5 S1c; 85 on target of the patients in the whole population with an endoxifen level 16 nM, in contrast to the absolute increase of 10 90 on target who benefits as in the base case